Mindblown: a blog about philosophy.
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Neural-fuzzy machine learning approach for the fatigue-creep reliability modeling of SAC305 solder joints
Weibull reliability distribution and ANOVA analysis The experiment was performed with seven replicates in each condition, and the fatigue life data were collected when the solder joints underwent complete failure. A two-parameter Weibull distribution was implemented to analyze the reliability performance at each experimental condition based on the obtained fatigue life. The fatigue life was…
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Artificial intelligence for improved fitting of trajectories of elementary particles in dense materials immersed in a magnetic field
Hasert, F. et al. Search for elastic muon-neutrino electron scattering. Phys. Lett. B 46, 121–124 (1973). Article ADS Google Scholar Hasert, F. et al. Observation of neutrino-like interactions without muon or electron in the Gargamelle neutrino experiment. Nucl. Phys. B 73, 1–22 (1974). Article ADS Google Scholar Chatrchyan, S. et al. Observation of a new…
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TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation
Plasmids Plasmids encoding His-ubiquitin, V5-TRABID, V5-TRABID C443S, and V5-VPS34 were described previously37. cDNAs for wild type TRABID and TRABIDΔN/CS (Δ1-32; C443S) were cloned to pRK5F and pLAS5w. Plasmid encoding GFP-Aurora B was kindly provided by Tang K Tang (Academia Sinica, Taipei, Taiwan), whereas plasmids encoding pLuc-IFNβ, pTK-Renilla, V5-cGAS, and Myc-Flag-STING were gifts from Li-Chung Hsu…
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Nationwide analysis of hospital admissions and outcomes of patients with SARS-CoV-2 infection in Austria in 2020 and 2021
Study design and setting This study was a retrospective analysis of data collected according to national legislation by Austrian hospitals and compiled by the Austrian National Public Health Institute (Gesundheit Österreich GmbH, GÖG). Anonymous data were provided to the study group by GÖG following approval of an open public data request directed to https://datenplattform-covid.goeg.at/. The…
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RNA ligase ribozymes with a small catalytic core
Oligonucleotides The oligo DNAs and RNAs were purchased from Sigma-Genosys or Eurofins with cartridge purification. The sequences are provided in Table 3. Table 3 Oligo DNA/RNA sequences. One-round selection of Lib-N7/8 Libraries with 7 degenerate bases (N7) and 8 degenerate bases (N8) were prepared separately, and they were mixed in 1:4 ratio so that each…
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Unprecedented recent regional increase in organic carbon and lithogenic fluxes in high altitude Pyrenean lakes
Anderson, N. J., Dietz, R. D. & Engstrom, D. R. Land-use change, not climate, controls organic carbon burial in lakes. Proc. R. Soc. B. 280, 20131278 (2013). Article CAS PubMed PubMed Central Google Scholar Anderson, N. J., Heathcote, A. J., Engstrom, D. R., Globocarb data contributors. Anthropogenic alteration of nutrient supply increases the global freshwater…
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Exercise-based rehabilitation on functionality and quality of life in head and neck cancer survivors. A systematic review and meta-analysis
Sherrod, A. M. et al. Caregiving burden in head and neck cancer. J. Clin. Oncol. 32, suppl 15 (2014). Mishra, A. & Meherotra, R. Head and neck cancer: Global burden and regional trends in India. Asian Pacific J. Cancer Prevent. https://doi.org/10.7314/APJCP.2014.15.2.537 (2014). Article Google Scholar Aupérin, A. Epidemiology of head and neck cancers: An update.…
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Evolution of surface area and membrane shear modulus of matured human red blood cells during mechanical fatigue
Shape transitions of RBCs during mechanical cycling In the present experimental data obtained, RBCs were from the fingertip blood of several healthy adult donners. Under the microscope, we found that discoid biconcave-shaped RBCs constituted the largest portion, and cup-shaped cells made up almost all of the remaining portion, while rare-shaped RBCs such as acanthocytes are…
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Anonymizing peer review makes the process more just
Keeping reviewers from seeing author names, affiliations and locations resulted in a fairer peer-review process.Credit: Proxima Studio/Shutterstock When manuscript authors’ identities and affiliations are blocked from peer reviewers, unconscious bias is less likely to influence peer review than when that information is available, a study finds. The research1 finds that ecology manuscripts by authors from…
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To diversify the scientific workforce, postdoc recruitment needs a rethink
Devang Mehta was hired through an ‘open’ faculty-recruitment programme.Credit: Kaat Hebbelinck It’s been known for nearly half a century that the ‘chilly climate’ of science higher education can make some students of colour feel unwelcome1. Since then, the shortage of people from minority groups in science, technology, engineering, and mathematics (STEM) fields has captured public…
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