Category: 6. Chemistry
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A new era in drug development
Graphical abstract of cyclic oral peptides. Credit: Christian Heinis/EPFL For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require specificity for particular protein homologs. Typically, larger biologics that can target these proteins…
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Enantiomeric lead-free double perovskites rationally designed by achiral-chiral cation intercalation
Schematic diagram of achiral-chiral cation intercalation strategy for designing a series of chiral lead-free halide double perovskites. Credit: Prof. Luo’s group Chiral optical materials have attracted great attention in multiple disciplines due to their wide application value in fields such as remote sensing, three-dimensional display, information communication, and optical information storage. With the strong demand for stable…
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Novel strategy stabilizes zinc-ion batteries
The schematic diagrams for Zn deposition in different electrolytes. Credit: Li Zhaoqian According to a study published in Advanced Functional Materials, a research team led by Prof. Hu Linhua from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences found that adding disodium maleate (DMA) to the electrolyte of aqueous zinc-ion batteries…
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A validated LC–MS/MS method for simultaneous determination of key glucocorticoids in animal hair for applications in conservation biology
Materials and reagents Ultrapure water was produced by a Milli-Q water purification system (Merck Millipore, Darmstadt, Germany). Hypergrade isopropanol, acetonitrile, formic acid, and acetic acid were from Merck (Darmstadt, Germany), and methanol was from POCH (Gliwice, Poland). Standards of cortisol, cortisone, corticosterone, and cortisol-D4 were from Sigma-Aldrich (Saint Louis, Missouri, USA). Stock and working solutions…
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Facile band gap tuning in graphene–brucite heterojunctions
Crystallographic considerations and smallest brucite/graphene interfaces We briefly introduce the symmetry of graphene and brucite Mg(OH)2, as it is fundamental for modelling the interface between the two materials. The former belongs to the \(P\overline{6 }m2\) space group, hexagonal crystal system, which is a subgroup of \(P{6}_{3}/mmc\), the space group of graphite (holohedral hexagonal space group).…
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Different spectrophotometric methods for simultaneous quantitation of Vericiguat and its alkaline degradation product: a comparative study with greenness profile assessment
Spectrophotometry is a widely used and essential technology in quality control tests throughout the world since the majority of compounds exhibit UV region absorption. However, it can be a challenge to identify the target compounds because molecules that are sensitive to degradation are frequently found alongside their degradation products and may have spectra that are…
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Study on the microcrystal cellulose and the derived 2D graphene and relative carbon materials
In this section the three MCC precursors are first carbonized in tube furnace at temperature 800 °C to 1400 °C in nitrogen atomosphere, respectively, then measured and characterized. Carbonization of sMCC The carbon product, carbonized from sMCC at tempereture1400 °C for 1 h, is labeled as sMCC-C. A notable phenomenon is that the sMCC-derived carbon sMCC-C keeps the shape…
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Microbial processes with the potential to mobilize As from a circumneutral-pH mixture of flotation and roaster tailings
Sandlos, J. & Keeling, A. Giant Mine: Historical Summary (Memorial University, 2012). Google Scholar Walker, S. R., Jamieson, H. E., Lanzirotti, A., Andrade, C. F. & Hall, G. E. M. The speciation of arsenic in iron oxides in mine wastes from the Giant gold mine, N.W.T.: Application of synchrotron micro-XRD and micro-XANES at the grain…
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Blessèd are the cheesemakers for their bacterial community shall show its worth | Research
Cooperative, as well as competitive, interactions between Streptococcus thermophilus and strains of Lactococcus have a key role in the development of flavour in cheddar cheese. Cheese fermentation and flavour formation are influenced by complex biochemical reactions driven by microbial activity and although the compositional dynamics of cheese microbiomes are relatively well mapped, the role of…
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Novel catalyst system for CO2 conversion
Research groups around the world are developing technologies to convert carbon dioxide (CO2) into raw materials for industrial applications. Most experiments under industrially relevant conditions have been carried out with heterogeneous electrocatalysts, i.e. catalysts that are in a different chemical phase to the reacting substances. However, homogeneous catalysts, which are in the same phase as…