Different spectrophotometric methods for simultaneous quantitation of Vericiguat and its alkaline degradation product: a comparative study with greenness profile assessment

Spectrophotometry is a widely used and essential technology in quality control tests throughout the world since the majority of compounds exhibit UV region absorption. However, it can be a challenge to identify the target compounds because molecules that are sensitive to degradation are frequently found alongside their degradation products and may have spectra that are highly overlapped. Direct spectrophotometry failed to estimate VER in its mixture with its alkaline degradation product as their absorption spectra exhibit a significant degree of interference. Thus, our main objective was…