Category: Nanotech
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Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours
Hou, A. J., Chen, L. C. & Chen, Y. Y. Navigating CAR-T cells through the solid-tumor microenvironment. Nat. Rev. Drug Discov. 20, 531–550 (2021). Article CAS Google Scholar Hong, M., Clubb, J. D. & Chen, Y. Y. Engineering CAR-T cells for next-generation cancer therapy. Cancer Cell 38, 473–488 (2020). Article CAS Google Scholar Chen, J.…
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Real-time monitoring of reaction stereochemistry through single-molecule observations of chirality-induced spin selectivity
Dalko, P. I. & Moisan, L. In the golden age of organocatalysis. Angew. Chem. Int. Ed. 43, 5138–5175 (2004). Article CAS Google Scholar Bornscheuer, U. T. et al. Engineering the third wave of biocatalysis. Nature 485, 185–194 (2012). Article CAS PubMed Google Scholar Hsieh, D. et al. Observation of unconventional quantum spin textures in topological…
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U.S. Universities Are Building a New Semiconductor Workforce
The CHIPS and Science Act, aimed at kick-starting chip manufacturing in the United States, only began taking requests for pieces of its US $50 billion in March, but chipmakers were already gearing up beforehand. Memory and storage chipmaker Micron announced as much as $100 billion for a new plant in upstate New York. Taiwan Semiconductor…
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Emergence of ferroelectricity in a nonferroelectric monolayer
Characterization of γ-GaSe The γ-GaSe has a hexagonal symmetric crystal structure with a = b = 3.75 Å, c = 24 Å, α = β = 90°, and γ = 120°, belonging to the R3m space group (\({C}_{3v}^{5}\))33,34,35. Few-layer GaSe nanoflakes were mechanically exfoliated from bulk using polydimethylsiloxane (PDMS) tape and then transferred onto SiO2/Si substrate. The Raman spectrum measured (Fig. 1b) on GaSe nanoflakes presents seven Raman active phonon…
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Comparative study of ternary hybrid nanofluids with role of thermal radiation and Cattaneo-Christov heat flux between double rotating disks
Here we investigate the effects of ternary hybrid nanofluid passing through a double disk. The Cattaneo-Christov heat flux theory is also taken into the investigation. We use Fe3O4, Cu, and SiO2 nanoparticles with Kerosene oil as the base fluid. The Maxwell model is employed to describe non-Newtonian fluid dynamics. Employing the proper similarity transformation, the…
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Machine learning for enhanced energy efficiency in fluctuating nanosystems
May 12, 2023 (Nanowerk News) Getting something for nothing doesn’t work in physics. But it turns out that, by thinking like a strategic gamer, and with some help from a demon, improved energy efficiency for complex systems like data centers might be possible. In computer simulations, Stephen Whitelam of the Department of Energy’s Lawrence Berkeley…
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Novel enhancer of inorganic nitrate’s protective effects, predicated on a swarm learning approach
A swarm learning-based drug combination prediction system identifying vitamin C as the optimal drug to be combined with sodium nitrate. This combination improved the bioavailability of sodium nitrate and exerted synergistic effects. Subsequently, the team used microencapsulation technology to prepare a nanoparticle named Nanonitrator, with sodium nitrate and vitamin C as its primary components. Nanonitrator…
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Carbon nanotube membranes with Pd-Cu modification successfully reduce nitrate levels via electrocatalysis
Graphical abstract. Credit: Frontiers of Environmental Science & Engineering (2022). DOI: 10.1007/s11783-023-1640-1 The adverse effects of excess nitrate in water on human productivity and lives have received increasing attention due to the discharge of industrial wastewater and the overuse of farmland fertilizers. An international team of researchers has conducted an in-depth study of the significant…
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Harnessing machine learning to make nanosystems more energy efficient
(a) We develop feedback-control protocols for an overdamped particle pulled by a harmonic potential and the Ising model undergoing magnetization reversal. (b) Feedback is enacted by a demon, a deep neural network, which controls the protocol to which the system is subjected by periodically taking in information from the system and outputting new values of the system’s…
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Multifunctional nanosystem effectively reverses multidrug resistance in tumors
Credit: Pixabay/CC0 Public Domain P-glycoprotein (P-gp/ABCB1) is a typical type of multiple drug resistance (MDR) transport protein that can recognize and promote the drug efflux of tumor cells, severely limiting the efficacy of anti-tumor drugs. BAY-1082439, a specific inhibitor against phosphatidylinositol-3-kinase (PI3K) 110α and 110β subunits, can reverse P-gp-mediated MDR by down-regulating… Continue Reading News…