A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy. A new, very precise gene-editing tool created by Weill Cornell Medicine investigators will enable scientists to study the impact of these specific genetic changes in preclinical models rather than being limited to more broadly targeted tactics, such as deleting the entire gene.
The tool was described in a study published Aug. 10 in Nature Biotechnology. Dr. Lukas Dow, an associate professor of…
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News Source: www.sciencedaily.com