Learning models for classifying Raman spectra of genomic DNA from tumor subtypes

In this section we describe the sample preparation procedures, the Raman measurements, and the statistical approaches developed to analyse the experimental data (see also^15,23).

Experimental procedures

Ag/SiNW substrate fabrication

Au catalyzed SiNWs have been grown on Si wafers by plasma enhanced chemical vapor deposition (PECVD) using SiH\(_4\) and H\(_2\) as precursors at a total pressure of 1 Torr and flow ratio SiH\(_4\)/(H\(_2+\)SiH\(_4\)), fixed to 1:10. The substrate temperature during the growth was kept at 350 °C, and a 13.6 MHz radiofrequency was used to ignite the plasma with…