Molecular system for an exponentially fast growing programmable synthetic polymer

We confirm exponential growth by measuring the conversion of monomers into a product. We then qualitatively measure the size of products over time. Finally, we verify the predicted structure using Atomic Force Microscopy.

Exponential growth mechanism controls

We tested each insertion step in the exponential growth mechanism by using the inactivated versions of of Hairpins 2 and 3 in which the binding loop is replaced by an inactive sequence of nucleotides (Fig. S3). Hairpin 2L and Hairpin 3L were added to the Initiator and Hairpin 1 both individually (this results in exactly one insertion…