Cross-modal autoencoder framework learns holistic representations of cardiovascular state

Our research complies with all relevant ethical regulations. Access was provided under UK Biobank application #7089. Analysis was approved by the Broad Institute institutional review board.

Study design

All analyses were performed on the UK Biobank, a prospective cohort of over 500,000 healthy adults that were aged 40–69 during enrollment, which took place from 2006 to 2010. At the time of our analysis the UK Biobank had released cardiovascular magnetic resonance imaging for over 44,644 participants, 38,686 of whom also had a 12-lead 10-second resting ECG acquired on the same day. The ECG…