Math unlocks molecular interactions that open window to how life evolved
A CRN containing the antithetic integral control motif as a subnetwork. a Closed-loop system for an antithetic integral controller (X1, X2), along with an interconnected auxiliary controller (X3, O1). Created with BioRender.com. b Chemical reactions for the CRN. c The CRN implements integral control via two independent internal models, corresponding to two independent polynomial invariants, each obtained by a linear change of coordinates. These are combined nonlinearly (through the concatenating monomial O1 applied to…
