New method illuminates druggable sites on proteins

Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the world. However, discovering how to alter the function of these proteins can be difficult, especially in live cells. Now, scientists from Scripps Research have developed a new method to examine how proteins interact with drug-like small molecules in human cells — revealing critical information about how to potentially target them therapeutically.

The strategy, published in Nature Chemical Biology on January 2, 2024, uses a combination of chemistry and analytical techniques to…

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News Source: www.sciencedaily.com


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