Elusive cytonemes guide neural development, provide signaling ‘express route’

St. Jude Children’s Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development. Cytonemes connect cells communicating across vast distances but are difficult to capture with microscopy in developing vertebrate tissues. The researchers are the first to find a way to visualize how cytonemes transport signaling molecules during mammalian nervous system development. The findings were published in Cell.

“We showed cytonemes are a direct express route for signal transport,” said corresponding author Stacey Ogden, PhD,…

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News Source: www.sciencedaily.com


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