Synaptic-like transmission between neural axons and arteriolar smooth muscle cells drives cerebral neurovascular coupling

Animal and animal care

All mice procedures complied with the Institutional Animal Care and Use Committee guidelines of the School of Life Sciences, Westlake University (approval no. 20-033-JJM). NG2DsRedBac, Thy1-YFP-H, Ai14 (Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}) and Ai96 (Gt(ROSA)26Sor^{tm96(CAG-GCaMP6s)Hze} mice (The Jackson Laboratory, stock nos. 008241, 003782, 007914 and 024106, respectively) were kindly provided by the laboratory of W.-p.G. at the Chinese Institute of Brain Research (CIBR). The laboratory of B.Z. kindly shared SMACreER (Tg(Sma-CreERT2)12Pcn) mice at the Shanghai Institutes…