CRISPR enhanced nanotweezers for ultra-precise DNA manipulation and detection

(Nanowerk News) Since the concept of optical trapping was first proposed in the 1960s and 1970s by Arthur Ashkin, researchers have pursued innovative techniques to precisely manipulate and analyze individual biomolecules like DNA. Such capabilities would revolutionize genetics, molecular biology, and medicine by enhancing our understanding of biological systems and enabling ultra-sensitive biosensing. However, progress has been hindered by the difficulty of selectively capturing nanoscale particles in liquid and identifying them. Now, scientists from Shenzhen…