Chromosomal instability in cancer cells causes DNA damage and promotes invasiveness: Study

In cells with high levels of chromosomal instability (in red), activation of the apoptotic caspases (in green) plays a fundamental role in tissue invasiveness. Credit: Dr. Mariana Muzzopappa, IRB Barcelona

Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division. It is very common in solid tumors and it is linked to the aggressive spread of cancer, that is to say, metastasis. Given that metastasis causes 90% of…

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News Source: phys.org