Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response

Reagents and antibodies Salvianolic acid C was purchased from Chengdu MUST biotechnology (Chengdu, China). Isoprenaline (I5627), 4′,6-diamidino-2-phenylindole (DAPI, D8417), heparin (H3393), Endothelial Cell Growth Supplement (ECGS, 211F-GS), glucose (G8769), verapamil (V4629), sulfapyridine (S6252), rotenone (R8875), antimycin A (A8674), digitonin (D141), malate (1613881), pyruvate (P2256), succinate (W327700), adenosine 5’-diphosphate (ADP, 1905), NADPH (NADPH-RO), Mito-tempo (SML0737), Pronase… Continue reading Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response

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Categorized as 8. Health

A neighbourly polar bear and a startled sloth: The best of the rest from the Wildlife Photographer of the Year 2022

The annual Wildlife Photographer of the Year competition is the most prestigious prize in its field, producing many famous winners and incredible stories for many years. This year’s prize is set to be no different. Ahead of the official prize winners being announced in October, the competition has just released a set of highly commended… Continue reading A neighbourly polar bear and a startled sloth: The best of the rest from the Wildlife Photographer of the Year 2022

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Categorized as General

James Webb space telescope captures new images of 'Phantom galaxy' – KTVB

James Webb space telescope captures new images of ‘Phantom galaxy’  KTVB Webb telescope captures ‘Phantom Galaxy’ in dazzling detail  FRANCE 24 English New photos reveal Phantom Galaxy in dazzling new light  New York Post NASA shares images of Phantom Galaxy  NEWS CENTER Maine View Full Coverage on Google News Continue Reading News Source: https://www.youtube.com/watch?v=z2Fpiu0opzs

Robots can be used to assess children’s mental well-being, study suggests

Credit: Rachel Gardner Robots can be better at detecting mental well-being issues in children than parent-reported or self-reported testing, a new study suggests. A team of roboticists, computer scientists and psychiatrists from the University of Cambridge carried out a study with 28 children between the ages of 8 and 13, and had a child-sized humanoid… Continue reading Robots can be used to assess children’s mental well-being, study suggests

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Categorized as 3. Tech

3D Orbital Architecture of a Dwarf Binary System and Its Planetary Companion

Numerical simulations suggest two main channels for the formation of multiple stellar systems: disk fragmentation (Adams et al. 1989), which produces secondaries through gravitational instability within a massive accretion disk, and turbulent fragmentation (e.g., Goodwin & Whitworth 2004; Fisher 2004), where turbulence in the original molecular core leads to multiple density enhancements, which independently collapse.… Continue reading 3D Orbital Architecture of a Dwarf Binary System and Its Planetary Companion

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Categorized as 2. Space

The Quadruple Image Configurations of Asymptotically Circular Gravitational Lenses

The simplest models for quadruply lensed quasars (henceforth quads) require seven parameters. Four of these are relatively uninteresting, governing position, angular orientation on the sky, and an overall scale. The interesting variations among different quads are due to the three remaining degrees of freedom. These three are straightforwardly parameterized by the x and y coordinates… Continue reading The Quadruple Image Configurations of Asymptotically Circular Gravitational Lenses

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Categorized as 2. Space

Constraining the Planet Occurrence Rate around Halo Stars of Potentially Extragalactic Origin

The search for planets orbiting other stars has recently expanded to include stars from galaxies outside the Milky Way. With the Transiting Exoplanet Survey Satellite (TESS) and Gaia surveys, photometric and kinematic information can be combined to identify transiting planet candidates of extragalactic origin. Here, 1080 low-luminosity red-giant branch stars observed by Gaia and TESS… Continue reading Constraining the Planet Occurrence Rate around Halo Stars of Potentially Extragalactic Origin

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Categorized as 2. Space

BD+47 378: An Eclipsing Binary Containing a δ Sct Pulsating Star

New high-resolution spectra of the eclipsing binary BD+47 378 were obtained on five nights between 2020 and 2021 with the Bohyunsan Observatory Echelle Spectrograph in Korea. We collected the TESS light curve of the system obtained from Sectors 17 to 18, which shows a flat bottom at the secondary eclipse, an O’Connell effect, and oscillation… Continue reading BD+47 378: An Eclipsing Binary Containing a δ Sct Pulsating Star

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Categorized as 2. Space

Intelsat’s Galaxy 15 mutes payload as its drifts into other satellite paths

TAMPA, Fla. — Intelsat said the Galaxy 15 broadcast satellite that stopped responding to commands earlier this month shut down its payload Aug. 31, reducing the risk of interfering with signals from other spacecraft. However, Galaxy 15 continues to drift out of its geostationary orbit slot at 133 degrees West, and “will soon begin transiting… Continue reading Intelsat’s Galaxy 15 mutes payload as its drifts into other satellite paths

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Categorized as 2. Space