Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort

1. Bonnie RJ, Fulco CE, Liverman CT, Institute of Medicine (US) Committee on Injury Prevention and Control. Reducing the burden of injury: advancing prevention and treatment. Washington, D.C.: National Academy Press; 1999. p. 319. 2. DiMaggio C, Ayoung-Chee P, Shinseki M, Wilson C, Marshall G, Lee DC, et al. Traumatic injury in the United States:… Continue reading Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort

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DNA-methylation dynamics across short-term, exposure-containing CBT in patients with panic disorder

1. Ninan PT, Dunlop BW. Neurobiology and etiology of panic disorder. J Clin Psychiatry. 2005;66:3–7. PubMed  Google Scholar  2. Goodwin RD, Faravelli C, Rosi S, Cosci F, Truglia E, De Graaf R, et al. The epidemiology of panic disorder and agoraphobia in Europe. Eur Neuropsychopharmacol. 2005;15:435–43. CAS  PubMed  Google Scholar  3. Wittchen HU, Jacobi F,… Continue reading DNA-methylation dynamics across short-term, exposure-containing CBT in patients with panic disorder

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Categorized as 5. Biology

Brain microRNAs are associated with variation in cognitive trajectory in advanced age

Study participants in the discovery and replication cohorts There were 454 ROS/MAP participants in the discovery analysis and 134 ROS/MAP participants in the replication analysis (Table 1). The main distinguishing feature between the discovery and replication cohorts is that the former has transcriptomic profiles, while the latter does not. Both the discovery and replication cohorts… Continue reading Brain microRNAs are associated with variation in cognitive trajectory in advanced age

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Categorized as 5. Biology

CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity

Prediction and screening of peptide candidates The interaction between the receptor-binding domain (RBD) of spike (S) protein and angiotensin-converting enzyme 2 (ACE2) underlies SARS-CoV-2 entry into host cells17,18. Several studies have shown that the RBD is an immunodominant region in the S protein, and neutralizing antibodies (NAbs) in convalescent patients’ sera are mostly against the… Continue reading CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity

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Categorized as 5. Biology

Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine

NAb response is enhanced by a third dose of inactivated SARS-CoV-2 vaccine BBIBP-CorV We have previously conducted a nonrandomized trial and recruited HCWs from a prospective cohort, demonstrating the impact of the circadian rhythm on the immune response induced by a primary two-dose series of the inactivated SARS-CoV-2 vaccine (BBIBP-CorV, Sinopharm, Beijing)11. Fifty HCWs from… Continue reading Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine

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Central corneal thickness and its determinants in a geriatric population: a population-based study

1. Chaudhry IA. Measurement of central corneal thickness in health and disease. Saudi J Ophthalmol. 2009;23:179–80. PubMed  PubMed Central  Google Scholar  2. Hashemi H, Yekta A, Saatchi M, Moravej R, Aghamirsalim M, Khabazkhoob M. The distribution of corneal thickness in rural population. Acta Med Iran. 2018;56:320–8. Google Scholar  3. Jonas JB, Stroux A, Oberacher-Velten IM,… Continue reading Central corneal thickness and its determinants in a geriatric population: a population-based study

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Categorized as 8. Health

Targeting mAKAPβ expression as a therapeutic approach for ischemic cardiomyopathy

1. Virani SS, Alonso A, Aparicio HJ, Benjamin EJ, Bittencourt MS, Callaway CW, et al. Heart Disease and Stroke Statistics-2021 update: a report From the American Heart Association. Circulation. 2021;143:e254–e743. PubMed  PubMed Central  Google Scholar  2. McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Bohm M, et al. 2021 ESC Guidelines for the… Continue reading Targeting mAKAPβ expression as a therapeutic approach for ischemic cardiomyopathy

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