Outer retinal transduction by AAV2-7m8 following intravitreal injection in a sheep model of CNGA3 achromatopsia

1. Zobor D, Zobor G, Kohl S. Achromatopsia: on the doorstep of a possible therapy. Ophthalmic Res. 2015;54:103–8. PubMed  Google Scholar  2. Zelinger L, Cideciyan AV, Kohl S, Schwartz SB, Rosenmann A, Eli D, et al. Genetics and disease expression in the CNGA3 form of achromatopsia: steps on the path to gene therapy. Ophthalmology. 2015;122:997–1007.… Continue reading Outer retinal transduction by AAV2-7m8 following intravitreal injection in a sheep model of CNGA3 achromatopsia

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Categorized as 5. Biology

Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons

1. Geevasinga N, Menon P, Ozdinler PH, Kiernan MC, Vucic S. Pathophysiological and diagnostic implications of cortical dysfunction in ALS. Nat Rev Neurol. 2016;12:651–61. CAS  PubMed  Google Scholar  2. Jara JH, Genc B, Klessner JL, Ozdinler PH. Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease.… Continue reading Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons

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Categorized as 5. Biology

The best personal care products of 2021

Our second year of making the most of too-much time spent at home has yielded countless products that promise to sooth our stressed minds and bodies. But the marketing around such spaces—cosmetics, skin- and haircare, and fitness, to name a few—is a minefield of meaningless buzzwords and pseudoscientific solutions. Our Personal Care winners represent some… Continue reading The best personal care products of 2021

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Categorized as General

How Income Inequality Can Drive COVID Infections

Latin American countries were quick to mandate lockdowns and mobility restrictions when COVID-19 hit in March 2020. While it was clear that these public health measures would put the brakes on the region’s growing economy, it was not evident how people would react to them, particularly when faced with the choice between sacrificing income and… Continue reading How Income Inequality Can Drive COVID Infections

Financial incentives help pregnant women to quit smoking

Credit: CC0 Public Domain Pregnant women are more likely to stop smoking if financial incentives are offered as part of a treatment plan, finds a trial from France published in The BMJ today. The results show that rewarding women for their smoking abstinence with vouchers throughout their pregnancy was associated with an increase in continuous… Continue reading Financial incentives help pregnant women to quit smoking

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Categorized as 8. Health

New tool helps people decide how best to protect themselves and others from COVID-19

A transmission electron micrograph of SARS-CoV-2 virus particles (UK B.1.1.7 variant), isolated from a patient sample and cultivated in cell culture. Credit: NIAID A new interactive graphic developed by UK researchers and published by The BMJ today will help people decide what to do in everyday situations to protect themselves, and others, from COVID-19. Based… Continue reading New tool helps people decide how best to protect themselves and others from COVID-19

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Categorized as 8. Health

Researchers Use Ultrasound to Remove Diseased Brain Cells

Researchers have developed a noninvasive method to remove faulty brain circuits using ultrasound and microbubbles. The corresponding research paper came from a collaboration of scientists at Stanford University and the University of Virginia School of Medicine and will be published in the Journal of Neurosurgery.  At present, removing faulty brain cells either involves invasive surgery-… Continue reading Researchers Use Ultrasound to Remove Diseased Brain Cells

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Categorized as 5. Biology

Biden administration turns focus to space security

As concerns grow about military threats to U.S. satellites, DoD’s top space policy post remains unfilled WASHINGTON — At the first meeting of the Biden administration’s National Space Council Dec. 1, Vice President Kamala Harris said a top concern is keeping space safe for military, civilian and commercial operations.   Harris said efforts to establish “rules… Continue reading Biden administration turns focus to space security

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Categorized as 2. Space

Next-gen Air Force pilot helmets are almost here

This story originally featured on Task & Purpose. Pilots of fixed-wing Air Force aircraft have been wearing the same helmet for nearly 40 years, but that could soon change with a new brain bucket that’s lighter, more comfortable, more adaptable and better ventilated than its predecessor, the HGU-55/P. “It’s been 40 years since we’ve had… Continue reading Next-gen Air Force pilot helmets are almost here

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Categorized as 3. Tech