Pfizer COVID-19 vaccine elicits durable specific memory T-cell response

While the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly and extensively throughout the world, its impact has been uneven. At present, it is estimated that about 50% of the world’s people are immune to the virus as a result of natural infection or vaccination; however, the occurrence of breakthrough infections has raised questions about the duration of immune protection.

A new preprint describes the protective efficacy of memory T-cells developed in response to the viral antigen, which could offer long-term immunity.

Study: BNT162b2 Vaccination Induces Durable SARS-Cov-2 Specific T Cells with A Stem Cell Memory Phenotype. Image Credit: Imilian /


The earliest vaccines against the coronavirus disease 2019…

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