The Genetic Mechanism of Male Infertility

Scientists may have finally figured out a genetic cause of male infertility.

Researchers at Newcastle University in the United Kingdom published their study in Nature Communications in early January 2022. Led by Professor Joris Veltman, the Dean of Newcastle University’s Biosciences Institute, the team investigated the potential genetic causes of male infertility. They found 145 rare, protein-affecting mutations that are the likely culprits.

Infertility experts estimate that 7% of people with male reproductive organs have male infertility, causing approximately half of the infertility issues experienced by heterosexual couples. 50% of these male infertility cases have unexplained causes. Identifying genetic causes of such a condition could help to explain this phenomenon and…

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