Investigating Omicron’s fitness and replicative potential compared with earlier SARS-CoV-2 variants using organoids

Over 5.59 million people have died due to the devastating coronavirus disease 2019 (COVID-19) pandemic, which is still wreaking havoc on worldwide health systems. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent, was discovered in Wuhan, China, in late 2019. During the first months of human circulation, SARS-CoV-2 was genetically and antigenically reasonably stable, but variants that were more transmissible and/or evaded immunity developed in late 2020.


Study: SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium. Image Credit: mohdizuan/Shutterstock


The Alpha variant (clade B.1.1.7) was the first variant of concern (VOC), and it became the dominant variant internationally in early 2021. The Delta variant (clade…

Continue Reading


News Source: https://www.news-medical.net/news/20220124/Investigating-Omicrone28099s-fitness-and-replicative-potential-compared-with-earlier-SARS-CoV-2-variants-using-organoids.aspx