The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread across the world over the last two years. With substantial human reservoirs with limited immunity, many new SARS-CoV-2 variants and sublineages of these variants have arisen.
Study: SARS-CoV-2 within-host and in-vitro genomic variability and sub-genomic RNA levels indicate differences in viral expression between clinical and in-vitro cohorts.
Even individuals who have contracted coronavirus disease 2019 (COVID-19) previously, or have been vaccinated, are still at risk, as reports of reinfections and vaccine breakthrough infections increase daily. SARS-CoV-2 strains such as the Delta and Beta variants show significant mutations in the spike protein that can help them evade immune…
News Source: https://www.news-medical.net/news/20211130/Host-and-in-vitro-genomic-variability-of-SARS-CoV-2-and-its-variants.aspx