Study explores connections between COVID-19 severity and gene expression in immune cells

New research shows how genetic variations linked to severe cases of COVID-19 affect our immune cells.

The study, led by scientists at La Jolla Institute for Immunology (LJI), is one of the first in-depth look at the connections between COVID-19 severity and gene expression in many types of immune cells. This work could guide the development of new COVID-19 therapies to boost immune cell function.

Among their findings, the researchers report that a gene in a cell type called non-classical monocytes, which are part of the body’s “first responder” team of innate immune cells, could be a potential target for COVID-19 therapies.

“This study highlights the power of human genetics to uncover novel pathways linked to disease,” says LJI Professor Pandurangan Vijayanand, M.D.,…

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News Source: https://www.news-medical.net/news/20211121/Study-explores-connections-between-COVID-19-severity-and-gene-expression-in-immune-cells.aspx