Researchers use tiny worm to trace the development of human brain

Researchers at Sinai Health have used a tiny worm to track how an animal’s brain changes throughout its lifetime, shedding new light on how human brains develop.

In new research, out today in Nature, scientists from the Lunenfeld-Tanenbaum Research Institute (LTRI) at Sinai Health describe four basic patterns of how new connections are made in the brain of the nematode worm, Caenorhabditis elegans, or C. elegans.

This is the first time that an entire brain’s structure is deduced and compared across developmental stages, from birth to adulthood. These new findings have powerful implications for the fundamental rules that allow the brain’s developmental maturation to take place.”

Dr. Mei Zhen, Senior Investigator, Lunenfeld-Tanenbaum Research Institute

Zhen and…

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